Methyl iodide → N-(4-Methoxyphenyl)-2,4-dinitroaniline

HRID 1393608ノート

反応式

HRID 1393608 の反応式
[N+:1]([C:4]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)([O-:3])=[O:2].[C:21](=O)([O-])[O-].[K+].[K+].CI>CN(C)C=O>[N+:1]([C:4]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:21])=[CH:9][CH:8]=1)([O-:3])=[O:2]

参加物

5

反応物 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 38580814-(2,4-Dinitroanilino)phenol

生成物 1

HCID 260958N-(4-Methoxyphenyl)-2,4-dinitroaniline

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

1.43 g of 4-(2,4-dinitroanilino)phenol, 500 mg of potassium carbonate and 0.32 ml of methyl iodide were stirred in 5 ml of N,N-dimethylformamide for 2 days at 20° C. The mixture was poured onto water, extracted three times with ethyl acetate, the extracts were dried on sodium sulfate, concentrated by evaporation in a vacuum, and the residue was chromatographed on silica gel.

後処理

  1. additionThe mixture was poured onto water
  2. extractionextracted three times with ethyl acetate
  3. customthe extracts were dried on sodium sulfate
  4. concentrationconcentrated by evaporation in a vacuum
  5. customthe residue was chromatographed on silica gel

出典と根拠

ORDレコード
ord-aed33f363a99435c923858b1921c5c1d
出典データセット
uspto-grants-2008_03
特許番号
US07345075B2

反応ノート

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