Sodium Hydroxide → HCID 50997323、化合物
反応式
[CH3:1][C:2]1[C:7]([CH:8]([CH2:13][CH2:14][CH3:15])[C:9]([O:11]C)=[O:10])=[C:6]([C:16]2[CH:17]=[C:18]3[C:22](=[CH:23][CH:24]=2)[CH2:21][CH2:20][C:19]3=[O:25])[N:5]=[C:4]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[N:3]=1.[OH-].[Na+]>CO>[CH3:1][C:2]1[C:7]([CH:8]([CH2:13][CH2:14][CH3:15])[C:9]([OH:11])=[O:10])=[C:6]([C:16]2[CH:17]=[C:18]3[C:22](=[CH:23][CH:24]=2)[CH2:21][CH2:20][C:19]3=[O:25])[N:5]=[C:4]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[N:3]=1参加物
4
実験手順
This compound was prepared according to general method D from methyl 2-(4-methyl-6-(3-oxo-2,3-dihydro-1H-inden-5-yl)-2-phenylpyrimidin-5-yl)pentanoate (0.177 g; 0.282 mmol), sodium hydroxide 10N (0.282 mL; 2.82 mmol) in methanol (2.8 mL). Purification by preparative HPLC (HPLC method 1) furnished 0.0016 g (1.4%) of the title compound as a brown solid.