Methanol → HCID 53663529、化合物
反応式
C([O:8][C:9]([NH:11][CH2:12][CH2:13][S:14]([NH2:17])(=[O:16])=[O:15])=O)C1C=CC=CC=1.CO>[Pd].C(O)=O>[CH:9]([NH:11][CH2:12][CH2:13][S:14]([NH2:17])(=[O:16])=[O:15])=[O:8]参加物
5
実験手順
In a reaction flask, 10.3 g of 2-benzyloxyformamidoethylsulfonamide, 10% Pd/C (3.0 g) and 600 ml of methanol were added. The mixture was stirred at room temperature overnight under hydrogen atmosphere, added with 35 ml of formic acid, stirred for 30 min, filtered, and concentrated under a reduced pressure to obtain 5.6 g of oily product, yield 93%.
後処理
- stirringstirred for 30 min
- filtrationfiltered
- concentrationconcentrated under a reduced pressure
出典と根拠
- ORDレコード
- ord-295e840ebcbc4de99c2ded232ca6a24d
- 出典データセット
- uspto-grants-2014_12
- 特許番号
- US08916574B2
反応ノート
読み込み中…