Tetrahydrofuran → HCID 67230022、化合物
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:17]=[CH:18][C:19]=1[NH:20][CH3:21])[C:7]([NH:9][C:10]1[CH:15]=[CH:14][C:13]([Br:16])=[CH:12][CH:11]=1)=[O:8])([O-])=O.C1COCC1>CO>[NH2:1][C:4]1[CH:5]=[C:6]([CH:17]=[CH:18][C:19]=1[NH:20][CH3:21])[C:7]([NH:9][C:10]1[CH:11]=[CH:12][C:13]([Br:16])=[CH:14][CH:15]=1)=[O:8]参加物
4
実験手順
A mixture of 3-Nitro-N-(4-bromophenyl)-4-methylaminobenzamide (120 mg, 0.34 mmol), 10 ml THF, 10 ml MeOH and 30 mg 5%-Pt-on-carbon was stirred for 4 h under a hydrogen atmosphere (3.5 bar). The catalyst was removed by filtration and the mixture was concentrated and used in the next step without further purification.
後処理
- customThe catalyst was removed by filtration
- concentrationthe mixture was concentrated
- customused in the next step without further purification
出典と根拠
- ORDレコード
- ord-6bcec334eb1f4c9099e025f4351ea38b
- 出典データセット
- uspto-grants-2014_12
- 特許番号
- US08921405B2
反応ノート
読み込み中…