[C:1]([NH:4][C:5]1[C:14]([N+:15]([O-:17])=[O:16])=[CH:13][C:8]([C:9]([O:11][CH3:12])=[O:10])=[C:7]([O:18][CH3:19])[CH:6]=1)(=[O:3])[CH3:2].[CH3:20]S(OC)(=O)=O.C([O-])([O-])=O.[K+].[K+]>CN(C=O)C.[Cl-].[Na+].O>[CH3:19][O:18][C:7]1[CH:6]=[C:5]([N:4]([CH3:20])[C:1](=[O:3])[CH3:2])[C:14]([N+:15]([O-:17])=[O:16])=[CH:13][C:8]=1[C:9]([O:11][CH3:12])=[O:10]A mixture of methyl 4-acetamido-2-methoxy-5-nitrobenzoate (2.0 g; 7.5 mmol), methyl methanesulfonate (0.85 g; 7.7 mmol) and K2CO3 (2.0 g; 14.5 mmol) in DMF (20 mL) was stirred for 36 h at rt. The mixture was thereafter poured into brine and extracted with EtOAc. The combined extracts were washed with brine, dried over Na2SO4, filtered and concentrated to give the crude sub-title compound.
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