Salicylamide → 2-Propoxybenzamide
反応式
[C:1]([NH2:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].C[O-].[Na+].I[CH2:15][CH2:16][CH3:17]>C(O)C>[CH2:15]([O:4][C:3]1[CH:5]=[CH:6][CH:7]=[CH:8][C:2]=1[C:1]([NH2:10])=[O:9])[CH2:16][CH3:17]参加物
5
実験手順
A 130 gm. portion of salicylamide in 500 ml. of ethanol is reacted with 52.4 gm. of sodium methoxide and 164.9 gm. of 1-iodopropane by heating at reflux. The mixture is cooled, precipitated in 1500 ml. of water and the solid is recrystallized from hot ethanol giving o-propoxybenzamide.
後処理
- temperatureat reflux
- temperatureThe mixture is cooled
- customprecipitated in 1500 ml
- customof water and the solid is recrystallized from hot ethanol
出典と根拠
- ORDレコード
- ord-54406c68a1c64b7fa2be4b95cccfd99a
- 出典データセット
- uspto-grants-1981_02
- 特許番号
- USRE030511
反応ノート
読み込み中…