Acetic Acid → 10-Oxo-10H-pyridazino[6,1-b]quinazoline-2-carboxylic acid
反応式
Cl[C:2]1[N:7]=[N:6][C:5]([C:8]([OH:10])=[O:9])=[CH:4][CH:3]=1.[C:11]([OH:14])(=O)[CH3:12]>N1C=CC=CC=1>[O:14]=[C:11]1[C:12]2[CH:8]=[CH:5][CH:4]=[CH:3][C:2]=2[N:7]=[C:2]2[CH:3]=[CH:4][C:5]([C:8]([OH:10])=[O:9])=[N:6][N:7]12参加物
4
実験手順
A precipitate is obtained when a mixture of methyl anthraniliate (4.78 g, 31.6 mmol), 6-chloropyridazine-3-carboxylic acid (5.0 g, 31.6 mmol) and 50 ml of acetic acid is heated at reflux for 21 hrs; m.p. 246°-50° C. This crude material is recyrstallized from pyridine giving the anlytical sample, m.p. 239°-43° C. (dec.).
後処理
- customA precipitate is obtained when
- temperatureis heated
- temperatureat reflux for 21 hrs
出典と根拠
- ORDレコード
- ord-43a0cc5fc4d2482e8a8dc283a00e828f
- 出典データセット
- uspto-grants-1981_02
- 特許番号
- US04250177
反応ノート
読み込み中…