Water → 4,8-Dimethyl-deca-1,6-dien-3-ol

HRID 1414461ノート

反応式

HRID 1414461 の反応式
[CH3:1][CH:2]([CH2:5][CH:6]=[CH:7][CH:8]([CH3:11])[CH2:9][CH3:10])[CH:3]=[O:4].[CH:12]([Mg]Cl)=[CH2:13].O>O1CCCC1>[CH3:1][CH:2]([CH2:5][CH:6]=[CH:7][CH:8]([CH3:11])[CH2:9][CH3:10])[CH:3]([OH:4])[CH:12]=[CH2:13]

参加物

5

反応物 3

HCID 962WaterHCID 538397432,6-Dimethyl-oct-4-en-1-alHCID 178461836HCID 178461836、化合物

生成物 1

HCID 542471304,8-Dimethyl-deca-1,6-dien-3-ol収率 94%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

54 g (0.35 mole) of 2,6-dimethyl-oct-4-en-1-al are added in the course of 15 minutes to a solution of 0.4 mole of vinyl-magnesium chloride in 2 liters of tetrahydrofuran, whilst cooling with ice. After a reaction time of 30 minutes, the mixture is hydrolyzed with 40 ml of water, the organic phase is isolated and the solvent is distilled off. The reaction product is fractionated, giving 60 g of the above allyl alcohol (yield, 94% of theory). B.p. = 48°-52° C at 0.02 mm Hg; nD25 = 1.4591.

後処理

  1. temperaturewhilst cooling with ice
  2. customAfter a reaction time of 30 minutes
  3. customthe organic phase is isolated
  4. distillationthe solvent is distilled off

出典と根拠

ORDレコード
ord-dc95a4cd33f74c54bc31df8af529958e
出典データセット
uspto-grants-1977_01
特許番号
US04001336

反応ノート

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