Isopropylamine → HCID 21487924、化合物

HRID 1414620ノート

反応式

HRID 1414620 の反応式
[C:1]([C:9]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[O:11][C:10]=1[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH2:25][CH:26]2[O:28][CH2:27]2)=[CH:20][CH:19]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:29]([NH2:32])([CH3:31])[CH3:30]>>[C:1]([C:9]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[O:11][C:10]=1[C:18]1[CH:19]=[CH:20][C:21]([O:24][CH2:25][CH:26]([OH:28])[CH2:27][NH:32][CH:29]([CH3:31])[CH3:30])=[CH:22][CH:23]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 6363IsopropylamineHCID 21487960HCID 21487960、化合物

生成物 1

HCID 21487924HCID 21487924、化合物

実験手順

3-Benzoyl-2-[4'-(2,3-epoxypropoxy)phenyl]benzofuran (1.9 g., 5.2 mmol.) was dissolved in 30 ml. of freshly distilled isopropylamine and the mixture was heated in a stainless steel pressure bomb at 100° for 4.5 hours. The contents of the bomb were concentrated under reduced pressure to give the title compound. The title compound was dissolved in ether and an ethereal solution of hydrochloric acid was added to precipitate the corresponding hydrochloride salt, m.p. 53°-59°.

後処理

  1. concentrationThe contents of the bomb were concentrated under reduced pressure

出典と根拠

ORDレコード
ord-a6c6f7ef136d48d593f4261aab6050bf
出典データセット
uspto-grants-1977_01
特許番号
US04001426

反応ノート

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