Epibromohydrin → HCID 21488028、化合物

反応式

[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=2)=[O:7])=[CH:4][CH:3]=1.[CH2:26]([CH:28]1[O:30][CH2:29]1)Br>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:22]=[CH:21][C:20]([O:23][CH2:26][CH:28]3[O:30][CH2:29]3)=[CH:19][CH:18]=2)=[O:7])=[CH:24][CH:25]=1

参加物

反応物 2

HCID 18430Epibromohydrin

HCID 21488040HCID 21488040、化合物

生成物 1

HCID 21488028HCID 21488028、化合物

実験手順

When an equivalent amount of 3-p-chlorobenzoyl-2-p-hydroxyphenylbenzofuran was reacted with epibromohydrin as described in the procedure of Example 26 and the product 3-(4'-chlorobenzoyl)-2-[4'-(2,3-epoxypropoxy)phenyl]benzofuran thus formed was treated with isopropylamine as described in the procedure of Example 25, the title compound was obtained.

出典と根拠

ORDレコード: ord-7fe51d197b6f4325bdbe781514c2e656
出典データセット: uspto-grants-1977_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04001426

反応ノート

読み込み中…

参加物