Ammonia → 2-Methyl-N-(2-methylpropylidene)-1-propanamine

HRID 1415159ノート

反応式

HRID 1415159 の反応式
[CH:1](=O)[CH:2]([CH3:4])[CH3:3].[H][H].[NH3:8]>[Ni]>[CH:1](=[N:8][CH2:1][CH:2]([CH3:4])[CH3:3])[CH:2]([CH3:4])[CH3:3]

参加物

5

反応物 3

HCID 222Ammonia2 回HCID 6561IsobutyraldehydeHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 1112442-Methyl-N-(2-methylpropylidene)-1-propanamine

試薬・触媒・溶媒 1

HCID 935Nickel触媒2 回

反応条件

温度
-15 °C

実験手順

1000g isobutyraldehyde and about 100 g of a commercially available nickel containing carrier catalyst (containing about 52 to 53% by weight nickel, and employing chromium (3)-oxide as activator) are introduced into a 2 l three-necked flask, equipped with a gas inlet tube, a stirrer and a reflux condensor, and cooled to -15° C. Hydrogen and ammonia are introduced into the resulting suspension in a volume ratio of 1 : 1 and at a temperature of 90° C. 160 l of gas are introduced per hour. Altogether, 240 l hydrogen and 240 l gaseous ammonia are introduced. After termination of the reaction, the catalyst is separated by filtration. 889 g isobutylidene -- isobutylamine are obtained.

後処理

  1. additionare introduced into a 2 l three-necked flask
  2. customequipped with a gas inlet tube, a stirrer
  3. customAfter termination of the reaction
  4. customthe catalyst is separated by filtration

出典と根拠

ORDレコード
ord-4b424334f7f34067b02091a588876cb7
出典データセット
uspto-grants-1977_01
特許番号
US04003921

反応ノート

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