Hydrochloric Acid → HCID 53705343、化合物

HRID 1415218ノート

反応式

HRID 1415218 の反応式
[C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])(=[O:3])[CH3:2].[Cl:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[Cl:20])[CH:15]=O.N1CCOCC1.Cl>O.C(O)C>[Cl:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[Cl:20])[CH:15]=[CH:2][C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])=[O:3]

参加物

7

反応物 4

HCID 313Hydrochloric AcidHCID 8083MorpholineHCID 227103,4-DichlorobenzaldehydeHCID 3364732-Acetyl-1,3-cyclopentanedione

生成物 1

HCID 53705343HCID 53705343、化合物収率 37.4%

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

実験手順

2-Acetyl-1,3-cyclopentanedione (3.13 g.) was treated with 3,4-dichlorobenzaldehyde (4.36 g.) in 140 ml. of ethanol under reflux for 4 hours in the presence of 5 ml. of morpholine. After cooling, the reaction mixture was poured into 150 ml. of water containing 7 ml. of conc. hydrochloric acid. Deposited crystals were separated by filtration and washed with water, and dried. 2-(3,4-Dichlorocinnamoyl)-1,3-cyclopentanedione (2.48 g., 37%) was obtained which showed mp. 190°- 191° C. after recrystallization from dioxane.

後処理

  1. temperatureAfter cooling
  2. additionthe reaction mixture was poured into 150 ml
  3. customDeposited crystals were separated by filtration
  4. washwashed with water
  5. customdried

出典と根拠

ORDレコード
ord-0cc9c682c8d6438daabb77fa6f991bab
出典データセット
uspto-grants-1977_01
特許番号
US04003936

反応ノート

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