Ethyl 2-methylacetoacetate → HCID 20361925、化合物

HRID 1415592ノート

反応式

HRID 1415592 の反応式
[CH3:1][CH:2]([NH:10][NH2:11])[C:3]1[CH:8]=[CH:7][C:6]([CH3:9])=[CH:5][CH:4]=1.C([O:14][C:15](=O)[CH:16]([CH3:20])[C:17]([CH3:19])=O)C>C(O)C>[CH3:19][C:17]1[NH:11][N:10]([CH:2]([CH3:1])[C:3]2[CH:8]=[CH:7][C:6]([CH3:9])=[CH:5][CH:4]=2)[C:15](=[O:14])[C:16]=1[CH3:20]

参加物

4

反応物 2

HCID 701Ethyl 2-methylacetoacetateHCID 12489385HCID 12489385、化合物

生成物 1

HCID 20361925HCID 20361925、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

30 g of α-methyl-4-methylbenzylhydrazine in ethanol were added to a solution of 28.8 g (0.2 mol) of α-methylacetoacetic acid ethyl ester in 40 ml of ethanol under N2 gas; during the addition, the temperature rose to 70° C. After completion of the addition, the reaction mixture was heated for 2 hours under reflux.

後処理

  1. additionduring the addition
  2. customrose to 70° C
  3. additionAfter completion of the addition
  4. temperaturethe reaction mixture was heated for 2 hours
  5. temperatureunder reflux

出典と根拠

ORDレコード
ord-980ec19afbb04ebabc56918d75cb84e1
出典データセット
uspto-grants-1977_01
特許番号
US04005215

反応ノート

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