Trimethylsilyl cyanide → alpha-(4-Methoxyphenyl)-alpha-(4-methylthioanilino)acetonitrile

反応式

[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([CH:7]=[N:8][C:9]2[CH:14]=[CH:13][C:12]([S:15][CH3:16])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.C[Si]([C:23]#[N:24])(C)C>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:7]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([S:15][CH3:16])=[CH:11][CH:10]=2)[C:23]#[N:24])=[CH:17][CH:18]=1

参加物

反応物 2

HCID 82115Trimethylsilyl cyanide

HCID 21862760N-(4-Methoxybenzylidene)-4-methylthioaniline

生成物 1

HCID 21862854alpha-(4-Methoxyphenyl)-alpha-(4-methylthioanilino)acetonitrile

実験手順

Following a procedure similar to that described in Example 1(ii), but using N-(4-methoxybenzylidene)-4-methylthioaniline [prepared as described in step (i) above] and trimethylsilyl cyanide as starting materials, the title compound was obtained as a pale brown powder (yield 92%).

出典と根拠

ORDレコード: ord-fa33ea44b77a4391a936bae6e149642b
出典データセット: uspto-grants-1999_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05908858

反応ノート

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