Acrolein → 1-(4-Methylphenyl)-2-(4-sulfamoylphenyl)pyrrole

HRID 1415778ノート

反応式

HRID 1415778 の反応式
[CH3:1][C:2]1[CH:21]=[CH:20][C:5]([NH:6][CH:7]([C:10]2[CH:15]=[CH:14][C:13]([S:16](=[O:19])(=[O:18])[NH2:17])=[CH:12][CH:11]=2)[C:8]#N)=[CH:4][CH:3]=1.[CH:22]([CH:24]=C)=O>>[CH3:1][C:2]1[CH:21]=[CH:20][C:5]([N:6]2[CH:24]=[CH:22][CH:8]=[C:7]2[C:10]2[CH:15]=[CH:14][C:13]([S:16](=[O:19])(=[O:18])[NH2:17])=[CH:12][CH:11]=2)=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 7847AcroleinHCID 21862835alpha-(4-Methylanilino)-alpha-(4-sulfamoylphenyl)acetonitrile

生成物 1

HCID 218628301-(4-Methylphenyl)-2-(4-sulfamoylphenyl)pyrrole

実験手順

Following a procedure similar to that described in Example 1(iii), but using α-(4-methylanilino)-α-(4-sulfamoylphenyl)acetonitrile [prepared as described in step (ii) above] and acrolein as starting materials, the title compound was obtained as a pale brown powder (yield 28%), melting at 131-134° C.

出典と根拠

ORDレコード
ord-d8ec8db41ce64236bb9fe1ff5b0cc16f
出典データセット
uspto-grants-1999_06
特許番号
US05908858

反応ノート

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