Hydrochloric Acid → 3-Nitro-5-vinylbenzoic acid methyl ester
反応式
[CH3:1][O:2][C:3](=[O:19])[C:4]1[CH:9]=[C:8]([CH:10]=[CH:11][Si](C)(C)C)[CH:7]=[C:6]([N+:16]([O-:18])=[O:17])[CH:5]=1.Cl>C(#N)C>[CH3:1][O:2][C:3](=[O:19])[C:4]1[CH:9]=[C:8]([CH:10]=[CH2:11])[CH:7]=[C:6]([N+:16]([O-:18])=[O:17])[CH:5]=1参加物
4
実験手順
3-Nitro-5-(2-trimethylsilylvinyl)benzoic acid methyl ester (2.44 g, 8.71 mmol) was dissolved in acetonitrile (150 ml), the solution was heated to reflux temperature and HCl gas was bubbled through the solution until the starting material had disappeared according to HPLC analysis. The solution was allowed to cool and the solvent was removed by evaporation. The residue was >95% pure according to HPLC and was used without further purification. Yield: 2.02 g (89%).
後処理
- temperaturethe solution was heated
- customwas bubbled through the solution until the starting material
- temperatureto cool
- customthe solvent was removed by evaporation
- customwas used without further purification
出典と根拠
- ORDレコード
- ord-5a19b2cfdf1f4a75a6b2a1695005b892
- 出典データセット
- uspto-grants-1999_03
- 特許番号
- US05882628
反応ノート
読み込み中…