Oxalyl chloride → 2-Chloro-3-methylbenzoyl chloride
反応式
[Cl:1][C:2]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].C(Cl)(=O)C([Cl:15])=O>CCOC(C)=O.CN(C=O)C>[Cl:1][C:2]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([Cl:15])=[O:5]参加物
5
実験手順
To a suspension of 2-chloro-3-methylbenzoic acid (6.75 g, 39.39 mmol) [prepared as described above] in EtOAc were added a few drops of DMF and oxalyl chloride (5.1 ml, 1.5 eq.). After stirring the reaction mixture for 1.5 h, the solvent was removed in vacuo to give 2-chloro-3-methylbenzoyl chloride, which was used in the next step without further purification.
後処理
- customthe solvent was removed in vacuo
出典と根拠
- ORDレコード
- ord-286b45f3fc23487bb696affab69f9a35
- 出典データセット
- uspto-grants-1999_03
- 特許番号
- US05886178
反応ノート
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