Benzyl Bromide → HCID 69471538、化合物

HRID 1420132ノート

反応式

HRID 1420132 の反応式
[F:1][CH2:2][C:3]([NH2:5])=[S:4].[CH2:6]([Br:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>C(Cl)(Cl)Cl.CCOCC>[BrH:13].[CH2:6]([S:4][C:3](=[NH:5])[CH2:2][F:1])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

参加物

5

反応物 2

HCID 7498Benzyl BromideHCID 167372062-Fluorothioacetamide

生成物 1

HCID 69471538HCID 69471538、化合物収率 54%

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒HCID 6212Chloroform溶媒

実験手順

Fluorothioacetamide (3.39 g) and benzyl bromide (6.23 g) were refluxed in chloroform (40 ml), under nitrogen, for 16 h. After cooling, the mixture was diluted with ether (200 ml) and the resulting orange solid filtered off. The solid was washed with more ether and dried over P2O5 in vacuo to give 5.19 g of the desired product.

後処理

  1. temperatureAfter cooling
  2. filtrationthe resulting orange solid filtered off
  3. washThe solid was washed with more ether
  4. dry with materialdried over P2O5 in vacuo

出典と根拠

ORDレコード
ord-93a754e113f9425abbc9ad40dd8b8ff7
出典データセット
uspto-grants-1999_03
特許番号
US05889056

反応ノート

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