Water → HCID 11311579、化合物

HRID 1420768ノート

反応式

HRID 1420768 の反応式
[Na].[C:2]([O:6][CH3:7])(=[O:5])[CH2:3][SH:4].C1(S(O[CH:18]=[C:19]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[O:28][CH3:29])[C:20]#[N:21])(=O)=O)C=CC=CC=1.O>CO>[NH2:21][C:20]1[C:19]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[O:28][CH3:29])=[CH:18][S:4][C:3]=1[C:2]([O:6][CH3:7])=[O:5]

参加物

6

反応物 4

HCID 962WaterHCID 16907Methyl ThioglycolateHCID 5360545SodiumHCID 57066737alpha-(Phenylsulphonyloxymethylidene)-2-methoxyphenylacetonitrile

生成物 1

HCID 11311579HCID 11311579、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

11 mmol of sodium are dissolved in 100 ml of methanol. After cooling the reaction mixture using an ice bath, 4.5 mmol of methyl thioglycolate and then 3.7 mmol of the compound obtained in Step B are added. After 2 hours' reaction, 100 ml of water are added, bringing about the formation of a precipitate, which is filtered off and then dried, allowing the to expected product to be isolated.

後処理

  1. temperatureAfter cooling the reaction mixture
  2. additionare added
  3. filtrationis filtered off
  4. customdried
  5. customto be isolated

出典と根拠

ORDレコード
ord-6bb6e1869add43ff9cb4880ebd322549
出典データセット
uspto-grants-2000_06
特許番号
US06071945

反応ノート

読み込み中…