Water → 3-(Benzyloxy)-4-methoxybenzyl alcohol

HRID 1420775

反応式

HRID 1420775 の反応式
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[CH:12]=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[BH4-].[Na+].O>CO.CCOCC>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH2:12][OH:13])[CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

6

反応物 3

HCID 962WaterHCID 806713-Benzyloxy-4-methoxybenzaldehydeHCID 4311764Sodium borohydride

生成物 1

HCID 746223-(Benzyloxy)-4-methoxybenzyl alcohol

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 3283Diethyl Ether溶媒

実験手順

A solution of 0.35 mol of the compound obtained in Step 1 in 400 ml of methanol and 1.5 equivalents of sodium borohydride is stirred for 6 hours at ambient temperature and then 500 ml of acidified water are slowly added. The precipitate obtained is taken up in ether; the organic phase is subsequently extracted, dried, filtered and then evaporated off under reduced pressure, allowing the expected product to be isolated.

後処理

  1. customThe precipitate obtained
  2. extractionthe organic phase is subsequently extracted
  3. customdried
  4. filtrationfiltered
  5. customevaporated off under reduced pressure
  6. customto be isolated

出典と根拠

ORDレコード
ord-fc144128b9d74547bc6aca0d6074e7de
出典データセット
uspto-grants-2000_06
特許番号
US06071945

関連ノート

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