Citric Acid → ethyl (4R)-4-[(8-bromo-9-methoxy-1,2,3,4-tetrahydrophenanthridin-6-yl)oxy]-1-[(2S)-2-cyclohexyl-2-({[(2,2-dimethylpent-4-en-1-yl)oxy]carbonyl}amino)acetyl]-L-prolinate

反応式

Cl.[Br:2][C:3]1[C:16]([O:17][CH3:18])=[CH:15][C:14]2[C:5](=[C:6]([O:19][C@H:20]3[CH2:24][NH:23][C@H:22]([C:25]([O:27][CH2:28][CH3:29])=[O:26])[CH2:21]3)[N:7]=[C:8]3[C:13]=2[CH2:12][CH2:11][CH2:10][CH2:9]3)[CH:4]=1.[CH:30]1([C@H:36]([NH:40][C:41]([O:43][CH2:44][C:45]([CH3:50])([CH3:49])[CH2:46][CH:47]=[CH2:48])=[O:42])[C:37](O)=[O:38])[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]1.CCN(C(C)C)C(C)C.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.C(O)(=O)CC(CC(O)=O)(C(O)=O)O>CN(C=O)C.CN(C1C=CN=CC=1)C>[Br:2][C:3]1[C:16]([O:17][CH3:18])=[CH:15][C:14]2[C:5](=[C:6]([O:19][C@H:20]3[CH2:24][N:23]([C:37](=[O:38])[C@H:36]([CH:30]4[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]4)[NH:40][C:41]([O:43][CH2:44][C:45]([CH3:50])([CH3:49])[CH2:46][CH:47]=[CH2:48])=[O:42])[C@H:22]([C:25]([O:27][CH2:28][CH3:29])=[O:26])[CH2:21]3)[N:7]=[C:8]3[C:13]=2[CH2:12][CH2:11][CH2:10][CH2:9]3)[CH:4]=1