Formamidine acetate → HCID 178469266、化合物
反応式
C(O[C:4]([C:6]1[NH:7][C:8]([CH3:17])=[C:9]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:10]=1[NH2:11])=[O:5])C.C(O)(=O)C.[CH:22](N)=[NH:23]>CCO>[CH2:15]([O:14][C:12]([C:9]1[C:10]2[N:11]=[CH:22][N:23]=[C:4]([OH:5])[C:6]=2[NH:7][C:8]=1[CH3:17])=[O:13])[CH3:16]参加物
4
実験手順
A reaction flask equipped with a mechanical stirrer, a reflux condenser and a nitrogen bubbler is charged with EtOH (5000 mL), 3-amino-5-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester from example A2 (565.57 g; 2.50 mol) and formamidine acetate (1041.10 g; 10.00 mol). The well-stirred reaction mixture is heated to gentle reflux for five days under an atmosphere of nitrogen.
後処理
- customA reaction flask equipped with a mechanical stirrer, a reflux condenser
- customThe well-stirred reaction mixture
- temperatureis heated
- temperatureto gentle reflux for five days under an atmosphere of nitrogen
出典と根拠
- ORDレコード
- ord-5fae4d7756c441988f3c70d6ce64f316
- 出典データセット
- uspto-grants-2015_01
- 特許番号
- US08927557B2
反応ノート
読み込み中…