Bromomethylcyclopropane → 2-Bromo-1-(cyclopropylmethoxy)-4-(trifluoromethyl)benzene

反応式

[Br:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[OH:12].Br[CH2:14][CH:15]1[CH2:17][CH2:16]1>>[Br:1][C:2]1[CH:7]=[C:6]([C:8]([F:10])([F:11])[F:9])[CH:5]=[CH:4][C:3]=1[O:12][CH2:14][CH:15]1[CH2:17][CH2:16]1

参加物

反応物 2

HCID 81503Bromomethylcyclopropane

HCID 27611682-Bromo-4-(trifluoromethyl)phenol

生成物 1

HCID 670329472-Bromo-1-(cyclopropylmethoxy)-4-(trifluoromethyl)benzene

実験手順

Starting from commercially available 2-bromo-4-trifluoromethyl-phenol and bromomethyl-cyclopropane the title compound is obtained as colorless oil after distillation at 5×10−3 mbar.

出典と根拠

ORDレコード: ord-5d49f94e9ba04e8d8d638e7767cd33ba
出典データセット: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08927557B2

反応ノート

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