Trifluoroacetic acid → 1-(4-Chloro-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-(2,5-difluorophenyl)urea

反応式

[CH3:45][O:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[Cl:1][c:2]1[cH:3][c:4]([F:44])[c:5]([NH:32][C:33](=[O:34])[NH:35][c:36]2[c:37]([F:43])[cH:38][cH:39][c:40]([F:42])[cH:41]2)[cH:6][c:7]1-[c:8]1[c:9](=[O:31])[n:10]([CH2:29][CH3:30])[c:11]2[cH:12][c:13]([N:18]([CH3:19])[CH2:20][c:21]3[cH:22][cH:23][c:24]([O:25][CH3:26])[cH:27][cH:28]3)[n:14][cH:15][c:16]2[cH:17]1.[F:53][C:54]([F:55])([F:56])[C:57]([OH:58])=[O:59]>>[Cl:1][c:2]1[cH:3][c:4]([F:44])[c:5]([NH:32][C:33](=[O:34])[NH:35][c:36]2[c:37]([F:43])[cH:38][cH:39][c:40]([F:42])[cH:41]2)[cH:6][c:7]1-[c:8]1[c:9](=[O:31])[n:10]([CH2:29][CH3:30])[c:11]2[cH:12][c:13]([NH:18][CH3:19])[n:14][cH:15][c:16]2[cH:17]1