Ethyl 7-(7-Formyl-2,3-di-p-tolyl-5H-pyrrolo[2,3-b]pyrazin-5-yl)heptanoate (Intermediate C) (47 mg, 0.097 mmol) in EtOH (2 ml) was degassed with N2 treated with sodium borohydride (5.52 mg, 0.146 mmol) was added. After stirring at RT for 3 hours, the mixture was diluted with water (30 ml) and the pH was adjusted to pH 1 using 2M HCl. The aqueous portion was extracted with DCM (×3) and the combined extracts were concentrated under reduced pressure. Purification of the crude product by chromatography on silica eluting with 0-40% EtOAc in iso-hexane afforded the titled compound as an orange oil;
