Methanol → Methyl 5-bromo-3-methylthiophene-2-carboxylate

HRID 1432776ノート

反応式

HRID 1432776 の反応式
S(Cl)(Cl)=O.[Br:5][C:6]1[S:10][C:9]([C:11]([OH:13])=[O:12])=[C:8]([CH3:14])[CH:7]=1.[CH3:15]O>>[Br:5][C:6]1[S:10][C:9]([C:11]([O:13][CH3:15])=[O:12])=[C:8]([CH3:14])[CH:7]=1

参加物

4

反応物 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 181766635-Bromo-3-methylthiophene-2-carboxylic acid

生成物 1

HCID 53438912Methyl 5-bromo-3-methylthiophene-2-carboxylate

実験手順

After thionyl chloride was added to methanol, 5-bromo-3-methylthiophene-2-carboxylic acid was added thereto and the resulting solution was heated and refluxed to obtain methyl 5-bromo-3-methylthiophene-2-carboxylate. EI: 234, 236.

後処理

  1. additionwas added
  2. temperaturethe resulting solution was heated
  3. temperaturerefluxed

出典と根拠

ORDレコード
ord-ee3b2633ffc3488b8fc4da110dcdef8b
出典データセット
uspto-grants-2009_11
特許番号
US07612108B2

反応ノート

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