HCID 86594994、化合物 → Methyl 4-(methylsulfanyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxylate
反応式
[N:1](/[C:4](=[CH:9]\[C:10]1[C:11]([S:16][CH3:17])=[N:12][CH:13]=[CH:14][CH:15]=1)/[C:5]([O:7][CH3:8])=[O:6])=[N+]=[N-]>C1(C)C=C(C)C=C(C)C=1>[CH3:17][S:16][C:11]1[C:10]2[CH:9]=[C:4]([C:5]([O:7][CH3:8])=[O:6])[NH:1][C:15]=2[CH:14]=[CH:13][N:12]=1参加物
3
実験手順
A solution of methyl (2Z)-2-azido-3-[2-(methylthio)pyridin-3-yl]prop-2-enoate (1.00 g, 4.00 mmol) in mesitylene (50 mL) was heated at 160° C. for a period of 1 h. The reaction mixture was cooled to room temperature then to 0° C., the precipitate was filtered and washed with cold mesitylene to provide the title compound.
後処理
- filtrationto 0° C., the precipitate was filtered
- washwashed with cold mesitylene
出典と根拠
- ORDレコード
- ord-7b8b859217984d659ae9570d0b70b662
- 出典データセット
- uspto-grants-2009_11
- 特許番号
- US07618979B2
反応ノート
読み込み中…