Thiocyanic Acid → HCID 86735207、化合物

HRID 1439376

反応式

HRID 1439376 の反応式
[OH:1][CH:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH2:3][N:4]1[CH2:6][CH2:5]1.[N:13]#[C:14][SH:15]>O1CCOCC1>[S-:15][C:14]#[N:13].[NH:13]=[C:14]1[N:4]([CH2:3][CH:2]([OH:1])[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH2:6][CH2:5][S:15]1

参加物

4

反応物 2

HCID 781Thiocyanic AcidHCID 288341-Aziridineethanol, .alpha.-phenyl-

生成物 1

HCID 86735207HCID 86735207、化合物収率 96%

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

A solution of 1-hydroxy-1-phenyl-2-ethyleniminoethane (16.3 g) in dioxan (35 ml) was added dropwise and with stirring at 0° C to an aqueous solution of thiocyanic acid (200 ml of 1N solution). After the addition the mixture was stirred in the cold for 1 hour. It was then heated under reflux for 1 hour and the solution cooled. The desired compound crystallised in 96% yield, m.p. 160° C.

後処理

  1. additionAfter the addition the mixture
  2. temperatureIt was then heated
  3. temperatureunder reflux for 1 hour
  4. temperaturethe solution cooled
  5. customThe desired compound crystallised in 96% yield, m.p. 160° C.

出典と根拠

ORDレコード
ord-02459d4d0d8944cc95342dd3830824a8
出典データセット
uspto-grants-1977_11
特許番号
US04059588

関連ノート

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