反応式
[C:1](#[N:6])[CH2:2][CH2:3][CH:4]=[CH2:5].N1C=CC=CC=1.[CH3:13][OH:14].C[C:16](C)=[O:17]>[C]=O.[CH-]=O.[CH-]=O.[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[Co].[Co+2]>[CH3:13][O:14][C:16](=[O:17])[CH2:5][CH2:4][CH2:3][CH2:2][C:1]#[N:6]参加物
7
反応条件
- 温度
- 160 °C
実験手順
A mixture of 8.1 parts of 4-pentenonitrile, 1.4 parts of dicobalt octacarbonyl, 2.6 parts of pyridine, 8 parts of methanol and 30 parts of acetone is reacted in the same way as in Example 1. The pressure is brought to 200 bars by forcing in carbon monoxide at room temperature. The autoclave is heated to 160° C, the pressure is raised to 300 bars by forcing in further carbon monoxide, and the autoclave is shaken for two hours under these conditions. Fractional distillation of the material discharged from the autoclave gives 10.6 parts of 5-cyanovaleric acid methyl ester (75.1% of theory); boiling point 122°-124° C/11 mm Hg.
後処理
- customis reacted in the same way as in Example 1
- temperaturethe pressure is raised to 300 bars
- distillationFractional distillation of the material
出典と根拠
- ORDレコード
- ord-f9c20d1089c1415ba4841aa3e5adb3f6
- 出典データセット
- uspto-grants-1977_11
- 特許番号
- US04060543
関連ノート
読み込み中…