Water → 3-(Nitro-n-butylamino)benzophenone

HRID 1439788ノート

反応式

HRID 1439788 の反応式
Cl[C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][C:3]=1[N+:16]([O-])=O.[CH2:19](N)[CH2:20][CH2:21][CH3:22].O.[N+:25](C1C=C(C=CC=1NCCCC)C(C1C=CC=CC=1)=O)([O-:27])=[O:26]>C1(C)C=CC=CC=1>[N+:25]([N:16]([CH2:19][CH2:20][CH2:21][CH3:22])[C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:2]=1)[C:6]([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)=[O:7])([O-:27])=[O:26]

参加物

6

反応物 4

HCID 962WaterHCID 8007ButylamineHCID 417434-Chloro-3-nitrobenzophenoneHCID 6205244-n-Butylamino-3-nitrobenzophenone

生成物 1

HCID 205552293-(Nitro-n-butylamino)benzophenone

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

A mixture of 4-chloro-3-nitrobenzophenone (13.08 g.; 0.05 mole) and n-butylamine (10.97 g.; 0.15 mole) are refluxed and stirred for 4 hours. To the reaction mixture is added water (300 ml.) and toluene (200 ml.) and the toluene layer collected and dried over magnesium sulfate. The toluene solution is filtered and the toluene removed under vacuum to afford 11.4 g. of 3-nitro-4-n-butylaminobenzophenone.

後処理

  1. temperatureare refluxed
  2. customthe toluene layer collected
  3. dry with materialdried over magnesium sulfate
  4. filtrationThe toluene solution is filtered
  5. customthe toluene removed under vacuum
  6. customto afford 11.4 g

出典と根拠

ORDレコード
ord-e97de0f6d624432391909d664805b238
出典データセット
uspto-grants-1977_11
特許番号
US04060636

反応ノート

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