1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → Diethyl L-cystinate
反応式
Cl.[CH2:2]([O:4][C:5](=[O:19])[C@@H:6]([NH2:18])[CH2:7][S:8][S:9][CH2:10][C@H:11]([NH2:17])[C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH3:3].CN(CCCN=C=NCC)C>O>[CH2:2]([O:4][C:5](=[O:19])[C@@H:6]([NH2:18])[CH2:7][S:8][S:9][CH2:10][C@H:11]([NH2:17])[C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH3:3]参加物
4
実験手順
5 g of polymer (2) and 5.73 g of cystine diethyl ester hydrochloride are dissolved in 100 ml of water. 6 g of N-dimethylaminopropyl-N'-ethylcarbodiimide (EDC) are then dissolved in 5 ml of water and immediately added to the reaction mixture. The reaction is stopped after 3 hours and 200 ml of water are added. The precipitate is recovered by filtration, washed several times with water and then oven-dried under vacuum.