Benzaldehyde → N-Benzylidene(piperidin-4-yl)methanamine

HRID 1444096

反応式

HRID 1444096 の反応式
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:9][CH2:10][CH:11]1[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]1>C1(C)C=CC=CC=1>[NH:14]1[CH2:15][CH2:16][CH:11]([CH2:10][N:9]=[CH:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH2:12][CH2:13]1

参加物

4

反応物 2

HCID 240BenzaldehydeHCID 235274-(Aminomethyl)piperidine

生成物 1

HCID 11820173N-Benzylidene(piperidin-4-yl)methanamine

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

Benzaldehyde (4.6 g; 0.044 mol) was added dropwise to a solution of 4-aminomethylpiperidine (5.0 g; 0.044 mol) in toluene (20 ml). The solution thus obtained was stirred for 3 h at room temperature. Then the solvent was removed by evaporation at reduced pressure and the residue was taken up twice with toluene to give the desired product that was used as such without further purification.

後処理

  1. customThe solution thus obtained
  2. customThen the solvent was removed by evaporation at reduced pressure

出典と根拠

ORDレコード
ord-5924d5348ad944b5b28619e072e9943f
出典データセット
uspto-grants-2010_02
特許番号
US07662836B2

関連ノート

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