Acetic Acid → Benzenesulfonamide, N-(2,6-diethyl-4-nitrophenyl)-4-methyl-

HRID 1447822

反応式

HRID 1447822 の反応式
[N+:1]([O-:4])(O)=[O:2].[CH2:5]([C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([CH2:13][CH3:14])[C:8]=1[NH:15][S:16]([C:19]1[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][CH:20]=1)(=[O:18])=[O:17])[CH3:6].C(O)(=O)C.N([O-])=O.[Na+]>O>[CH2:5]([C:7]1[CH:12]=[C:11]([N+:1]([O-:4])=[O:2])[CH:10]=[C:9]([CH2:13][CH3:14])[C:8]=1[NH:15][S:16]([C:19]1[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][CH:20]=1)(=[O:17])=[O:18])[CH3:6]

参加物

6

反応物 4

HCID 176Acetic AcidHCID 944Nitric AcidHCID 7315352',6'-Diethyl-p-toluenesulfonanilideHCID 23668193Sodium Nitrite

生成物 1

HCID 155515Benzenesulfonamide, N-(2,6-diethyl-4-nitrophenyl)-4-methyl-

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To a solution of 115 ml nitric acid (d=1.42) in water (900 ml) are added successively 129.9 g (0.43 moles) of N-(2,6-diethylphenyl)-p-toluenesulfonamide, glacial acetic acid (900 ml) and sodium nitrite (3.2 g). The mixture is boiled on a steam bath for 1.5 hours, then poured into ice water (2 l). The precipitate is filtered washed with water and air-dried to give crude N-(2,6-diethyl-4-nitrophenyl)-p-toluenesulfonamide.

後処理

  1. filtrationThe precipitate is filtered
  2. washwashed with water
  3. customair-dried

出典と根拠

ORDレコード
ord-eaf66b6a56e2414c8c2ea42982328f74
出典データセット
uspto-grants-1979_12
特許番号
US04178387

関連ノート

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