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Dimethylformamide dimethyl acetal → 3-Dimethylamino-2-methyl-3'-(trifluoromethyl)acrylophenone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 反応物 | Propiophenone, 3'-(trifluoromethyl) | HCID 137064 | — |
| 生成物 | 3-Dimethylamino-2-methyl-3'-(trifluoromethyl)acrylophenone | HCID 54529942 | — |
反応手順
A mixture of 25 g. of m-trifluoromethylpropiophenone and 25 ml. of dimethylformamide dimethylacetal is refluxed overnight and then evaporated to an oil. The oil is dissolved in hexane and the solution is refrigerated giving crystals of the desired product, m.p. 53°-55° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04178449 |
| 出典データセット | uspto-grants-1979_12 |
| ORD ID | ord-f3127b22e1ac4643be4bf18e9fe40f1d |
| 出典メモ | uspto-grants-1979_12 |