Diisopropyl Ether → 2-[O-[N-methyl-(2,4-dimethyl-3-oxo-2-pentanesulfenyl)carbamoyl]oximino]-3,5,5-trimethylthiazolidin-4-one

HRID 1448080ノート

反応式

HRID 1448080 の反応式
[CH3:1][N:2]1[C:6](=[O:7])[C:5]([CH3:9])([CH3:8])[S:4][C:3]1=[N:10][OH:11].[CH3:12][N:13]([S:17][C:18]([CH3:25])([C:20](=[O:24])[CH:21]([CH3:23])[CH3:22])[CH3:19])[C:14](Cl)=[O:15].C(N(CC)CC)C.C(OC(C)C)(C)C>O1CCOCC1>[CH3:12][N:13]([S:17][C:18]([CH3:19])([C:20](=[O:24])[CH:21]([CH3:22])[CH3:23])[CH3:25])[C:14]([O:11][N:10]=[C:3]1[N:2]([CH3:1])[C:6](=[O:7])[C:5]([CH3:9])([CH3:8])[S:4]1)=[O:15]

参加物

6

反応物 4

HCID 7914Diisopropyl EtherHCID 8471TriethylamineHCID 54024146N-methyl-N-(2,4-dimethyl-3-oxo-2-pentanesulfenyl)carbamoyl chlorideHCID 713633892-(Hydroxyimino)-3,5,5-trimethyl-1,3-thiazolidin-4-one

生成物 1

HCID 542459562-[O-[N-methyl-(2,4-dimethyl-3-oxo-2-pentanesulfenyl)carbamoyl]oximino]-3,5,5-trimethylthiazolidin-4-one収率 39.6%

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

Prepared as in Example I by reacting 2.94 g (0.0169 m) of 3,5,5-trimethyl-2-oximino-thiazolidin-4-one, 4.0 g (0.0169 m) of N-methyl-N-(2,4-dimethyl-3-oxo-2-pentanesulfenyl)carbamoyl chloride and 1.7 g (0.0169 m) of triethylamine in 200 ml of dioxane. The productcrystallized from isopropyl ether to yield 2.5 g of a white solid, m.p. 112°-114° C.

後処理

  1. customPrepared as in Example I

出典と根拠

ORDレコード
ord-ac9267b951534875b221cd95cbc025f2
出典データセット
uspto-grants-1979_12
特許番号
US04179514

反応ノート

読み込み中…