Hydrochloric Acid → Phenol, 4-methoxy-2-nitro-

HRID 1448473ノート

反応式

HRID 1448473 の反応式
[N+:1]([C:4]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:5]=1N)([O-:3])=[O:2].[OH-].[Na+].[O:15]=[As]O[As]=O.Cl>O>[N+:1]([C:4]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:5]=1[OH:15])([O-:3])=[O:2]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 667934-Methoxy-2-nitroanilineHCID 261004Arsenic(III) oxide

生成物 1

HCID 15285Phenol, 4-methoxy-2-nitro-

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

336.4 g of 2-nitro-4-methoxyaniline was refluxed for 20 hours with 200 g of sodium hydroxide and 10 g of arsenic trioxide, in 6500 ml of water. The resulting solution was cooled on an ice-bath, then acidified to pH 1 with concentrated hydrochloric acid. The solid which formed was filtered and washed with water and dried under reduced pressure over P2O5 to give 2-nitro-4-methoxyphenol, 8A, m.p.: 78°-80°.

後処理

  1. temperatureThe resulting solution was cooled on an ice-bath
  2. customThe solid which formed
  3. filtrationwas filtered
  4. washwashed with water
  5. dry with materialdried under reduced pressure over P2O5

出典と根拠

ORDレコード
ord-af389d274af04fada2ae41a58d734204
出典データセット
uspto-grants-1979_12
特許番号
US04180572

反応ノート

読み込み中…