1-Butanaminium, N,N,N-tributyl-, azide → 1-Benzyl-3-trifluoromethyl-3-(azidomethyl)pyrrolidine

HRID 1450095

反応式

[CH2:1]([N:8]1[CH2:12][CH2:11][C:10]([C:25]([F:28])([F:27])[F:26])([CH2:13]OS(C2C(C)=CC=CC=2)(=O)=O)[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N-:29]=[N+:30]=[N-:31].C([N+](CCCC)(CCCC)CCCC)CCC>C(#N)C.C(Cl)Cl>[CH2:1]([N:8]1[CH2:12][CH2:11][C:10]([C:25]([F:28])([F:27])[F:26])([CH2:13][N:29]=[N+:30]=[N-:31])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

実験手順

The compound (2.43 g) from step 456c was dissolved in acetonitrile, then reacted with tetrabutylammonium azide at 80° C. for 16 hours. The mixture was diluted with methylene chloride, then washed with water and brine and dried. Removal of the solvent gave 0.751 g of the title compound.

後処理

washwashed with water and brine
customdried
customRemoval of the solvent

出典と根拠

ORDレコード: ord-3c4e7d40affa461d8caacef04405ca6a
出典データセット: uspto-grants-1997_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05599816

反応式

参加物

反応物 2

生成物 1

試薬・触媒・溶媒 2

実験手順

後処理

出典と根拠

関連ノート