Methanol → HCID 10464708、化合物
反応式
[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[CH2:3].CO.F[B-](F)(F)F.F[B-](F)(F)F.O[N+]12CC[N+]([F:31])(CC1)CC2.CC[O:34][CH2:35]C>C(#N)C>[F:31][CH2:3][C:2]([O:34][CH3:35])([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:1]参加物
6
実験手順
To a solution of alpha-methylstyrene (0.13 mL, 1 mmole)and methanol (0.05 mL, 1.1 mmole) in acetonitrile (10 mL) was added 1-hydroxyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) (330 mg, 1.02 mmole 1.02 equ.) and the reaction stirred at room temperature for 24 h. The mixture was diluted with ether (2 mL), filtered through anhydrous MgSO4, and evaporated to afford 130 mg (85% yield) of 1-fluoro-2-methoxy-2-phenylpropane.
後処理
- filtrationfiltered through anhydrous MgSO4
- customevaporated
出典と根拠
- ORDレコード
- ord-926391074d1d4b9b8fd64dadaa83f39e
- 出典データセット
- uspto-grants-1997_02
- 特許番号
- US05606084
反応ノート
読み込み中…