Hydrochloric Acid → HCID 68821142、化合物
反応式
[BH4-].[Na+].[CH3:3][N:4]1[C:9]2[S:10][CH:11]=[C:12]([CH3:13])[C:8]=2[S:7](=[O:15])(=[O:14])[N:6]=[CH:5]1.Cl>C(O)(C)C.O>[CH3:3][N:4]1[C:9]2[S:10][CH:11]=[C:12]([CH3:13])[C:8]=2[S:7](=[O:15])(=[O:14])[NH:6][CH2:5]1参加物
6
反応条件
- 温度
- 50 °C
実験手順
240 mg of sodium borohydride are added to 120 mg of the compound obtained in Step B above dissolved in 6 ml of isopropanol. The mixture is heated at 50° C. for 10 minutes. The solvent is removed under reduced pressure, then the residue that is obtained is taken up in 5 ml of water. The pH of the solution is adjusted to 4 by addition of 6N hydrochloric acid. The precipitate is collected by filtration, washed with water and dried.
後処理
- customThe solvent is removed under reduced pressure
- customthe residue that is obtained
- filtrationThe precipitate is collected by filtration
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-1e0c8f53fcb549ba97834d9fd9464be4
- 出典データセット
- uspto-grants-2009_01
- 特許番号
- US07476668B2
反応ノート
読み込み中…