Isoamylamine → HCID 11754033、化合物
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]#[C:9][C:10]2[CH:31]=[CH:30][C:13]([O:14][CH2:15][CH2:16][NH:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([CH2:25]NCCC)=[CH:21][CH:20]=3)=[CH:12][CH:11]=2)=[CH:4][CH:3]=1.[CH2:32]([NH2:37])[CH2:33][CH:34]([CH3:36])[CH3:35]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]#[C:9][C:10]2[CH:11]=[CH:12][C:13]([O:14][CH2:15][CH2:16][NH:17][CH2:18][C:19]3[CH:20]=[CH:21][C:22]([CH2:25][NH:37][CH2:32][CH2:33][CH:34]([CH3:36])[CH3:35])=[CH:23][CH:24]=3)=[CH:30][CH:31]=2)=[CH:4][CH:3]=1参加物
3
実験手順
Compound 5 was synthesized using the procedure described for Compound 2 except that isoamylamine was used in the final reductive amination step. Compound 5 was obtained as a white solid. MS 462; 1H NMR (CDCl3) δ 4.10 (t, 2H), 3.86 (s, 2H), 3.77 (s, 2H), 3.03 (t, 2H), 2.63 (t, 2H), 0.89 (d, 6H).
後処理
- customCompound 5 was synthesized
出典と根拠
- ORDレコード
- ord-550310d36e244280b96b90586a5dc8c2
- 出典データセット
- uspto-grants-2009_01