関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Morpholine | HCID 8083 | — |
| 反応物 | 2-Chloro-1-fluoro-4-nitrobenzene | HCID 67688 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Morpholine, 4-(2-chloro-4-nitrophenyl)- | HCID 108711 | — |
反応手順
1.76 g (10.0 mmol) 3-chloro-4-fluoro-1-nitro-benzene are combined with 2.614 ml (30 mmol) morpholine in 5 ml DMF and heated to 105° C. with stirring for 15 min. The reaction mixture is poured into ice water, the resulting precipitate is suction filtered, washed with water and dried at 50° C. in the drying cupboard.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07476663B2 |
|---|
| 出典データセット | uspto-grants-2009_01 |
|---|
| ORD ID | ord-45b69a4754604d009d53bf22411bdd7c |
|---|
| 出典メモ | uspto-grants-2009_01 |
|---|
