Sodium Hydroxide → 5-Cyclopropylmethoxymethyl-6-methyl-pyridin-2-ylamine
反応式
[CH:1]1([CH2:4][O:5][CH2:6][C:7]2[CH:8]=[CH:9][C:10]([NH:14]C(=O)C(C)(C)C)=[N:11][C:12]=2[CH3:13])[CH2:3][CH2:2]1.[OH-].[Na+]>>[CH:1]1([CH2:4][O:5][CH2:6][C:7]2[CH:8]=[CH:9][C:10]([NH2:14])=[N:11][C:12]=2[CH3:13])[CH2:3][CH2:2]1参加物
3
実験手順
This material was prepared in analogy to example 86 step B] from N-(5-cyclopropylmethoxymethyl-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide (0.357 g) and 3M aqueous NaOH (2.68 mL) as a dark red oil (0.163 g). MS (EI): 192.2 (M+).
出典と根拠
- ORDレコード
- ord-4cd94311109942f087bb4cee0b685f0b
- 出典データセット
- uspto-grants-2009_01
- 特許番号
- US07482341B2
反応ノート
読み込み中…