Sodium Hydroxide → 5-(2-Fluoro-ethoxymethyl)-6-methyl-pyridin-2-ylamine
反応式
[F:1][CH2:2][CH2:3][O:4][CH2:5][C:6]1[CH:7]=[CH:8][C:9]([NH:13]C(=O)C(C)(C)C)=[N:10][C:11]=1[CH3:12].[OH-].[Na+]>>[F:1][CH2:2][CH2:3][O:4][CH2:5][C:6]1[CH:7]=[CH:8][C:9]([NH2:13])=[N:10][C:11]=1[CH3:12]参加物
3
実験手順
This material was prepared in analogy to example 86 step B] from N-[5-(2-Fluoro-ethoxymethyl)-6-methyl-pyridin-2-yl]-2,2-dimethyl-propionamide (0.165 g) and 3M aqueous NaOH (1.23 mL) as an gum (0.174 g) that was used directly in the next step.
出典と根拠
- ORDレコード
- ord-980289a6aa99450a8c7ae76245de99f2
- 出典データセット
- uspto-grants-2009_01
- 特許番号
- US07482341B2
反応ノート
読み込み中…