Water → Ethyl cyclobut-1-ene-1-carboxylate
反応式
[C:1]1([C:5]([OH:7])=[O:6])[CH2:4][CH2:3][CH:2]=1.[CH2:8](I)[CH3:9].C(=O)([O-])[O-].[K+].[K+].O>CN(C)C=O>[CH2:8]([O:6][C:5]([C:1]1[CH2:4][CH2:3][CH:2]=1)=[O:7])[CH3:9]参加物
6
実験手順
To a solution of 3.2425 g (33.09 mmol) of 1-cyclobutenecarboxylic acid in 60 ml of dimethylformamide were added 12 ml (150 mmol) of ethyl iodide and 5.53 g (40 mmoL) of potassium carbonate, followed by 20 hours of stirring at room temperature. The reaction solution was poured into water and extracted with ether. The organic layer was washed with water and saturated brine and then dried over anhydrous sodium sulfate. By evaporating the solvent, 4.5267 g of the title compound was obtained as a mixture with ethyl iodide and ether.
後処理
- extractionextracted with ether
- washThe organic layer was washed with water and saturated brine
- dry with materialdried over anhydrous sodium sulfate
- customBy evaporating the solvent
出典と根拠
- ORDレコード
- ord-1b2f6fa95d1f4c8387d29fba12d691d0
- 出典データセット
- uspto-grants-1998_12
- 特許番号
- US05849757
反応ノート
読み込み中…