反応式
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[CH:4][N:3]=1.[CH3:9][C@H:10]1[CH2:15][CH2:14][CH2:13][C@@H:12]([CH3:16])[NH:11]1>>[Cl:8][C:6]1[CH:7]=[C:2]([N:11]2[C@H:12]([CH3:16])[CH2:13][CH2:14][CH2:15][C@@H:10]2[CH3:9])[N:3]=[CH:4][N:5]=1参加物
3
実験手順
0.5 g of 4,6-dichloropyrimidine and 0.76 g of cis-2,6-dimethylpiperidine were mixed and stirred for 10 hours at 90%. The reaction mixture was subjected to silica gel column chromatography to obtain 0.21 g of 4-chloro-6-(cis-2,6-dimethylpiperidino)pyrimidine.
出典と根拠
- ORDレコード
- ord-f5e9b66fe77449749982e038ebebf7e4
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07732448B2
関連ノート
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