Isobutyl chloride → 2-Isopropyl-5-nitrobenzofuran

反応式

[Br-].[OH:2][C:3]1[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[CH:25][C:4]=1[CH2:5]P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[CH2:32](Cl)[CH:33]([CH3:35])[CH3:34]>>[CH:33]([C:35]1[O:2][C:3]2[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[CH:25][C:4]=2[CH:5]=1)([CH3:34])[CH3:32]

参加物

反応物 2

HCID 10554Isobutyl chloride

HCID 178526701HCID 178526701、化合物

生成物 1

HCID 544749412-Isopropyl-5-nitrobenzofuran

実験手順

Reaction of 2-hydroxy-5-nitrobenzyl triphenylphosphine bromide (prepared as described in Example 1(a) (40 g, 0.08 mol) and isobutyl chloride (10,6, 0.1. mol) was carried out with the method described in Example 1(b) to produce 19.7 g of 2-isopropyl-5-nitrobenzofuran.

後処理

customprepared

出典と根拠

ORDレコード: ord-619f38cb936a4a90b63a1621d3d358db
出典データセット: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05854282

反応ノート

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