Ethanol → 2-Nitro-5-(4-acetylamino-1-piperidyl)benzaldehyde

HRID 1460678

反応式

HRID 1460678 の反応式
C[O:2][CH:3](OC)[C:4]1[CH:9]=[C:8]([N:10]2[CH2:15][CH2:14][CH:13]([NH:16][C:17](=[O:19])[CH3:18])[CH2:12][CH2:11]2)[CH:7]=[CH:6][C:5]=1[N+:20]([O-:22])=[O:21].C=O.C(O)C>Cl.O>[N+:20]([C:5]1[CH:6]=[CH:7][C:8]([N:10]2[CH2:11][CH2:12][CH:13]([NH:16][C:17](=[O:19])[CH3:18])[CH2:14][CH2:15]2)=[CH:9][C:4]=1[CH:3]=[O:2])([O-:22])=[O:21]

参加物

6

反応物 3

HCID 702EthanolHCID 712FormaldehydeHCID 190868632-Nitro-5-(4-acetylamino-1-piperidyl)benzaldehyde dimethylacetal

生成物 1

HCID 190868462-Nitro-5-(4-acetylamino-1-piperidyl)benzaldehyde

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid触媒HCID 962Water溶媒

実験手順

0.3 Gram of 2-nitro-5-(4-acetylamino-1-piperidyl)benzaldehyde dimethylacetal, 5 ml of formalin, 1 ml of ethanol and 2 drops of concentrated hydrochloric acid were refluxed by heating. After the reaction was completed, the solvent was removed by evaporation to obtain the residue, then water was added to the residue. The crystals formed were collected by filtration to yield 0.22 g of 2-nitro-5-(4-acetylamino-1-piperidyl)benzaldehyde.

後処理

  1. temperatureby heating
  2. customthe solvent was removed by evaporation
  3. customto obtain the residue
  4. customThe crystals formed
  5. filtrationwere collected by filtration

出典と根拠

ORDレコード
ord-a500e6d154d94be0b110e84b4341736f
出典データセット
uspto-grants-1991_12
特許番号
US05071856

関連ノート

読み込み中…