Thionyl Chloride → Acetyl chloride, (benzoyloxy)-

HRID 1461116ノート

反応式

HRID 1461116 の反応式
[C:1]([O:9][CH2:10][C:11]([OH:13])=O)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:16])=O>>[C:1]([O:9][CH2:10][C:11]([Cl:16])=[O:13])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 12647149HCID 12647149、化合物

生成物 1

HCID 10888895Acetyl chloride, (benzoyloxy)-収率 88%

実験手順

A mixture of 2-(benzoyloxy)acetic acid (12.6 g) and thionyl chloride (15 ml) was refluxed for 3 h. Excess of thionyl chloride was removed in vacuo and the crude (benzoyloxy)acetyl chloride obtained was purified by distillation in vacuo. The yield was 88%. Mp 25°-26° C.

後処理

  1. temperaturewas refluxed for 3 h
  2. customExcess of thionyl chloride was removed in vacuo

出典と根拠

ORDレコード
ord-894768fca82143b29a962f66aa2071e8
出典データセット
uspto-grants-1991_12
特許番号
US05073641

反応ノート

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