Potassium Nitrate → HCID 178526418、化合物

HRID 1461307ノート

反応式

HRID 1461307 の反応式
[N+:1]([O-:4])([O-])=[O:2].[K+].[OH:6][C:7]1[C:16]([OH:17])=[N:15][C:14]2[C:9](=[CH:10][CH:11]=[C:12]3[N:20]=[CH:19][S:18][C:13]3=2)[N:8]=1>S(=O)(=O)(O)O>[OH:6][C:7]1[C:16]([OH:17])=[N:15][C:14]2[C:9](=[CH:10][C:11]([N+:1]([O-:4])=[O:2])=[C:12]3[N:20]=[CH:19][S:18][C:13]3=2)[N:8]=1

参加物

4

反応物 2

HCID 24434Potassium NitrateHCID 178517010HCID 178517010、化合物

生成物 1

HCID 178526418HCID 178526418、化合物収率 63.1%

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

Finely powdered potassium nitrate (92 mg, 0.9 mmol) was added to a stirred and ice-cooled solution of 7,8-dihydroxythiazolo[5,4-f]quinoxaline (0.20 g, 0.9 mmol) in 5 ml of conc. sulfuric acid. The mixture was stirred at 0° C. for 30 min, then at room temperature for 4 h, and finally poured into ice/water. The resulting precipitate was isolated by filtration, washed with water, and dried giving 0.15 g (62%) of the nitro compound; m.p.>360° C., IR (KBr): 1680 cm-1 ; 1H-NMR (DMSO-d6): 8.06 (s, 1H, ArH), 9.53 (s, 1H, ArH), 12.23 (broad s, 1H, OH), 12.76 (broad s, 1H, OH).

後処理

  1. stirringThe mixture was stirred at 0° C. for 30 min
  2. customThe resulting precipitate was isolated by filtration
  3. washwashed with water
  4. customdried

出典と根拠

ORDレコード
ord-3b0d44ae824d48e7a9e7c8040afdc709
出典データセット
uspto-grants-1991_12
特許番号
US05075306

反応ノート

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