Succinimide → N-(2-cycloheptenyl)succinimide
反応式
Br[CH:2]1[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]=[CH:3]1.[C:9]1(=[O:15])[NH:13][C:12](=[O:14])[CH2:11][CH2:10]1.[Na].C1(=O)NC(=O)CC1.[H-].[Na+]>O.CN(C=O)C>[CH:2]1([N:13]2[C:9](=[O:15])[CH2:10][CH2:11][C:12]2=[O:14])[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]=[CH:3]1参加物
7
実験手順
3-Bromocycloheptene (1.75 g) was added dropwise at room temperature to a DMF suspension (10 ml) of sodium succinimide prepared from succinimide (0.99 g) and 60% sodium hydride (0.40 g). This mixture was stirred at room temperature for 24 hours, poured into water (10 ml) and extracted with ether. The oily product obtained by concentration was purified by chromatography on silica gel to obtain 0.09 g of N-(2-cycloheptenyl)succinimide [Compound (214)].
後処理
- extractionextracted with ether
- customThe oily product obtained by concentration
- customwas purified by chromatography on silica gel
出典と根拠
- ORDレコード
- ord-89b0334f9dac473ca34ed80919c6c267
- 出典データセット
- uspto-grants-1991_12
- 特許番号
- US05075488
反応ノート
読み込み中…